Team Idea
BioSynthetix: Protein Mutation & Target Binding Screening Agent
The Problem: Early-stage biotech research requires jumping between complex structural prediction scripts (like ESMFold) and literature searches, leaving wet-lab scientists bogged down in command-line tools.
An interactive computational biology copilot that accelerates drug-target discovery:
Structural Prediction on ROCm: Serves Meta’s ESM-2 / ESMFold protein language models directly on AMD compute to evaluate point-mutation stability in seconds.
Binding Affinity Screener: Predicts molecular docking efficacy against candidate ligands.
Scientific Synthesis Agent: Pulls live citations from PubMed and ChEMBL to cross-reference known binding inhibitors and draft an audit report detailing candidate viability.
3D Molecular Viewer: An interactive, browser-based 3D protein visualizer (using Mol* or 3Dmol.js) showing binding pockets and residue alterations.